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LRRC32 Antikörper (AA 301-500)

LRRC32 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7172807
  • Target Alle LRRC32 Antikörper anzeigen
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-500
    Reaktivität
    • 29
    • 13
    • 9
    • 1
    Human
    Wirt
    • 19
    • 16
    • 4
    • 1
    Kaninchen
    Klonalität
    • 20
    • 20
    Polyklonal
    Konjugat
    • 20
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser LRRC32 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 14
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
    Isotyp
    IgG
    Top Product
    Discover our top product LRRC32 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Andere Bezeichnung
    LRRC32 (LRRC32 Produkte)
    Synonyme
    D11S833E antikoerper, GARP antikoerper, AI426318 antikoerper, D11S833Eh antikoerper, D7H11S833E antikoerper, EG434215 antikoerper, Garp antikoerper, leucine rich repeat containing 32 antikoerper, LRRC32 antikoerper, Lrrc32 antikoerper
    Hintergrund

    Background: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).

    Aliases: D11S833E antibody, GARP antibody, Garpin antibody, Glycoprotein A repetitions predominant antibody, Leucine rich repeat containing 32 antibody, Leucine-rich repeat-containing protein 32 antibody, LRC32_HUMAN antibody, LRRC32 antibody

    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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