MAPT Antikörper

Produktnummer ABIN5541353

Dieser Huhn Polyklonal Antikörper detektiert spezifisch MAPT in WB, IF, ICC und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für MAPT Antikörper (ABIN5541353)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reaktivität: Human, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser MAPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MAPT Antikörper

Spezifität: Specific for the ~48, 65 & 75 kDa Tau isoforms.

Aufreinigung: Ig Fraction

Immunogen: Recombinant full length Human Tau expressed in and purified from E. coli.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blotting: 1/10,000. Immunohistochemistry. Immunofluorescence: 1/1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservatives: 10 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Andere Bezeichnung: mapt,tau

Hintergrund: Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy.

UniProt: P10636

Pathways: MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size