ICOSLG Antikörper (Extracellular Domain)

Produktnummer ABIN5541150

Der Maus Monoklonal Anti-ICOSLG Antikörper wurde für FACS und EIA validiert. Er ist geeignet, ICOSLG in Proben von Human zu detektieren.

Kurzübersicht für ICOSLG Antikörper (Extracellular Domain) (ABIN5541150)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICOSLG Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: GM13C1

Produktdetails anti-ICOSLG Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody recognizes Human CD275 / ICOS Ligand. Other species not tested.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Genetic immunisation with cDNA encoding Human ICOSL (Extracellular Domain).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Andere Bezeichnung: cd275,icos ligand

Hintergrund: Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS)(1). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secre-tion (2,3).

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation