SPTAN1 Antikörper
Kurzübersicht für SPTAN1 Antikörper (ABIN5540660)
Target
Alle SPTAN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Specific for the ~240 k alpha II Spectrin protein.
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Aufreinigung
- Affinity Chromatography
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Immunogen
- Recombinant construct containing the seventh, eighth and ninth repeats of human alpha II spectrin expressed in and purified from E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- Western Blot: 1/3000. Immunofluorescence: 1/500.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS Preservatives: 10 mM Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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Andere Bezeichnung
- spectrin alpha chain (brain),sptan1
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Hintergrund
- The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004).
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UniProt
- P07751
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Pathways
- Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization
Target
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