PTPRT Antikörper (AA 1-742)

Produktnummer ABIN5540588

Produktdetails anti-PTPRT Antikörper

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Bindungsspezifität: AA 1-742

Reaktivität: Human, Ratte, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTPRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: Monoclonal antibodies 3G4 and 3D7 have been directed against the extracellular domain of RPTPμ.

Aufreinigung: Purified

Immunogen: This antibody has been derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPmu molecule (aa 1-742), fused COOH terminally to GST.

Klon: 3D7

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PTPRT

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Andere Bezeichnung: ptprt (PTPRT Produkte)

Synonyme: RPTPrho antikoerper, RPTP-rfo antikoerper, mKIAA0283 antikoerper, protein tyrosine phosphatase, receptor type T antikoerper, protein tyrosine phosphatase, receptor type, T antikoerper, PTPRT antikoerper, Ptprt antikoerper

Hintergrund: Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substrates. RPTPμ is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPμ consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPμ is catalytically active, whereas its second (C-terminal) domain is inactive. RPTPμ is involved in cell-cell adhesion through homophilic interactions and may also play a key role in signal transduction and growth control.

UniProt: O14522