PTPRT Antikörper (Middle Region)
Kurzübersicht für PTPRT Antikörper (Middle Region) (ABIN2789504)
Target
Alle PTPRT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- PTPRT Antibody - middle region
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Sequenz
- QQFQFLGWPM YRDTPVSKRS FLKLIRQVDK WQEEYNGGEG RTVVHCLNGG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PTPRM. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PTPRT
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63449-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))
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Andere Bezeichnung
- PTPRT
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Hintergrund
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Background Information: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Gene Name: protein tyrosine phosphatase, receptor type T
Alternative Symbols: R-PTP-T, RPTPrho, RPTP-rho
Protein Name: receptor-type tyrosine-protein phosphatase T
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Molekulargewicht
- 30kDa
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Gen-ID
- 11122
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NCBI Accession
- NP_008981
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UniProt
- O14522
Target
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