PTPRT Antikörper (AA 200-280)

Produktnummer ABIN7230850

Der Kaninchen Polyklonal anti-PTPRT Antikörper wird verwendet zum Nachweis von PTPRT in Proben von Human und Maus. Er wurde validiert für ELISA und WB.

Kurzübersicht für PTPRT Antikörper (AA 200-280) (ABIN7230850)

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRT Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-PTPRT Antikörper

Bindungsspezifität: AA 200-280

Verwendungszweck: Rabbit Anti-PTPRT Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PTPRT protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PTPRT protein at AA range: 200-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PTPRT

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Andere Bezeichnung: PTPRT

Hintergrund: Receptor-type tyrosine-protein phosphatase T, R-PTP-T, Receptor-type tyrosine-protein phosphatase rho, RPTP-rhoThe protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRT possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of PTPRT suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of PTPRT, which encode distinct proteins, have been reported.

Molekulargewicht: 158kD

Gen-ID: 11122

UniProt: O14522