IL13 Receptor alpha 1 Antikörper (Extracellular Domain)

Produktnummer ABIN5540414

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL13 Receptor alpha 1 in IF, ICC, FACS und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL13 Receptor alpha 1 Antikörper (Extracellular Domain) (ABIN5540414)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL13 Receptor alpha 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: GM1E7

Produktdetails anti-IL13 Receptor alpha 1 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Recognizes IL13 Receptor (IL13-R).

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Genetic immunization with cDNA encoding Human IL13-R alpha 1 (extracellular domain). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1 μg/10 Specific inhibition of IL-13-dependent proliferation of TF-1 cells by GM-1E7 (See Figure.3).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Andere Bezeichnung: cd213a1,il13ra1

Hintergrund: Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation

UniProt: P78552

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response