GFRA3 Antikörper

Produktnummer ABIN5540354

Dieses Huhn Polyklonal-Antikörper erkennt spezifisch GFRA3 in WB, IF, EIA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GFRA3 Antikörper (ABIN5540354)

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser GFRA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

Produktdetails anti-GFRA3 Antikörper

Spezifität: This antibody detects Human GFRa-3 and doesn't cross-react with hGFRa-1, hGFRa-2, hGFRa-4. Other species not tested.

Aufreinigung: Affinity Chromatography

Immunogen: Recombinant His-tagged human GFRa-3 protein produced using CHO-based. For production of hGFRa-3, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: ELISA: 1/160000-1/320000. Western blot: 1/5000-1/10000. Immunofluorescence: 1/500-1/3000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Concentrated Ammonium Sulphate in PBS pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt, store at 2-8°C. As product is (NH4) 2 SO 4 precipitate, mix well by pipetting or vortexing prior use. Shelf life: One year from despatch.

Details zu GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Andere Bezeichnung: gfra3,gdnfr-alpha 3

Hintergrund: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).

UniProt: O60609