GFRA3 Antikörper (Intermediate Domain)

Produktnummer ABIN499887

Der Kaninchen Polyklonal anti-GFRA3 Antikörper (ABIN499887) detektiert spezifisch GFRA3 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GFRA3 Antikörper (Intermediate Domain) (ABIN499887)

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GFRA3 Antikörper

Bindungsspezifität: Intermediate Domain

Spezifität: GFR alpha 3 antibody was raised against a peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.

Aufreinigung: DEAE

Immunogen: Human GFR alpha 3 (Intermediate Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/500 to 1/1000. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Andere Bezeichnung: GFRA3 / GDNFR-alpha 3

Hintergrund: Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta (2). Following the findings of GFR?-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.Synonyms: GDNF family receptor alpha-3, GDNF receptor alpha-3, GFR-alpha-3

Gen-ID: 14587

UniProt: O35118