AGPS Antikörper (AA 158-384)
Kurzübersicht für AGPS Antikörper (AA 158-384) (ABIN5540330)
Target
Alle AGPS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 158-384
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Spezifität
- This antibody recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis.
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Aufreinigung
- Protein-A affinity chromatography (>95% pure by SDS-PAGE)
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Immunogen
- Recombinant human AGPS (amino acids 158-384)
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Isotyp
- IgG2a
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Applikationshinweise
- Flow cytometry. Western blot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- AGPS (Alkylglycerone Phosphate Synthase (AGPS))
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Andere Bezeichnung
- agps,aag5
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Hintergrund
- AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
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UniProt
- O00116
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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