AGPS Antikörper (AA 158-384)
Kurzübersicht für AGPS Antikörper (AA 158-384) (ABIN2749041)
Target
Alle AGPS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 158-384
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Verwendungszweck
- Anti-AGPS Purified
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- recombinant human AGPS (amino acids 158-384)
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Isotyp
- IgG2a
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Applikationshinweise
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Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/mL. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- AGPS (Alkylglycerone Phosphate Synthase (AGPS))
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Andere Bezeichnung
- AGPS
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Hintergrund
- Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY
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Gen-ID
- 8540
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UniProt
- O00116
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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