AGPS Antikörper (AA 158-384) (APC)

Produktnummer ABIN7505837

Der APC-konjugierte Maus Monoklonal anti-AGPS Antikörper (Klon AGPS-03) (ABIN7505837) detektiert spezifisch AGPS in ICFC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AGPS Antikörper (AA 158-384) (APC) (ABIN7505837)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AGPS Antikörper ist konjugiert mit APC

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: AGPS-03

Produktdetails anti-AGPS Antikörper (APC)

Bindungsspezifität: AA 158-384

Verwendungszweck: Anti-AGPS APC

Produktmerkmale: The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human AGPS (amino acids 158-384)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze,Protect from prolonged exposure to light

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Andere Bezeichnung: AGPS

Hintergrund: Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY

Gen-ID: 8540

UniProt: O00116

Pathways: SARS-CoV-2 Protein Interaktom