AGPS
Reaktivität: Ratte
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Flow cytometry. Western blot.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
AGPS
(Alkylglycerone Phosphate Synthase (AGPS))
Andere Bezeichnung
agps,aag5
Hintergrund
AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.