CD44 Antikörper (PE)

Produktnummer ABIN5540180

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD44 in FACS. Es zeigt Reaktivität gegenüber Proben von Pferd. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für CD44 Antikörper (PE) (ABIN5540180)

Target: CD44

Reaktivität: Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: CVS18

Produktdetails anti-CD44 Antikörper (PE)

Spezifität: Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker. Species: Equine (Horse).

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Equine leucocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry : Neat, use 10 μL to label 10 6 cells in 100 μL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-CD44 Antikörper (PE) (ABIN5540180)

Carrade, Lame, Kent, Clark, Walker, Borjesson: "Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells()." in: Cell medicine, Vol. 4, Issue 1, pp. 1-11, (2012) (PubMed).

Radcliffe, Flaminio, Fortier: "Temporal analysis of equine bone marrow aspirate during establishment of putative mesenchymal progenitor cell populations." in: Stem cells and development, Vol. 19, Issue 2, pp. 269-82, (2010) (PubMed).

Schneider, Essmann, Kletke, Rio, Hanenberg, Wetzel, Schulze-Osthoff, Nürnberg, Piekorz: "The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29273-83, (2007) (PubMed).

Details zu CD44

Target: CD44

Andere Bezeichnung: cd44

Hintergrund: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

UniProt: Q05078

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling