NGFR Antikörper (AA 1-160) (Biotin)
Kurzübersicht für NGFR Antikörper (AA 1-160) (Biotin) (ABIN5540156)
Target
Alle NGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-160
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Spezifität
- This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
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Immunogen
- Purified CD271 protein isolated from human melanoma cell line A875
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Isotyp
- IgG1
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Applikationshinweise
- Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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Andere Bezeichnung
- cd271,ngfr
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Hintergrund
- CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
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UniProt
- P08138
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
Target
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