CD40 Ligand Antikörper

Produktnummer ABIN5540106

Produktdetails anti-CD40 Ligand Antikörper

Target: CD40 Ligand (CD40LG)

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Functional Studies (Func)

Spezifität: This antibody detects CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes.

Aufreinigung: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogen: Human CD154 fusion protein

Klon: 24-31

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry. Immunocytochemistry. Functional application: blocking.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: cd154,cd40l (CD40LG Produkte)

Synonyme: CD154 antikoerper, cd40l antikoerper, CD40L antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TNFSF5 antikoerper, TRAP antikoerper, gp39 antikoerper, hCD40L antikoerper, CD40-L antikoerper, Cd40l antikoerper, Ly-62 antikoerper, Ly62 antikoerper, Tnfsf5 antikoerper, CD40 ligand antikoerper, TNF superfamily member 5 antikoerper, CD40LG antikoerper, cd40l antikoerper, Cd40lg antikoerper

Hintergrund: CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.

UniProt: P29965

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints