ASXL1 Antikörper (AA 521-549)

Produktnummer ABIN5535502

Der Kaninchen Polyklonal anti-ASXL1 Antikörper (ABIN5535502) detektiert spezifisch ASXL1 in WB, FACS, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für ASXL1 Antikörper (AA 521-549) (ABIN5535502)

Target: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ASXL1 Antikörper

Bindungsspezifität: AA 521-549

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ASXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ASXL1

Target: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Andere Bezeichnung: ASXL1

Hintergrund: This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 165 kDa

Gen-ID: 171023

UniProt: Q8IXJ9

Pathways: Retinoic Acid Receptor Signaling Pathway