ASXL1 Antikörper

Produktnummer ABIN930987

Produktdetails anti-ASXL1 Antikörper

Target: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ASXL1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: ASXL1 antibody was raised in mouse using recombinant Human Additional Sex Combs Like 1 (Drosophila) (Asxl1)

Klon: 2049C2a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: ASXL1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu ASXL1

Target: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Andere Bezeichnung: ASXL1 (ASXL1 Produkte)

Synonyme: asxl1 antikoerper, MGC83850 antikoerper, mKIAA0978 antikoerper, BOPS antikoerper, MDS antikoerper, additional sex combs like 1, transcriptional regulator L homeolog antikoerper, additional sex combs like 1, transcriptional regulator antikoerper, additional sex combs like 1 antikoerper, asxl1.L antikoerper, ASXL1 antikoerper, asxl1 antikoerper, Asxl1 antikoerper

Hintergrund: This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. Synonyms: Monoclonal ASXL1 antibody, Anti-ASXL1 antibody, Additional sex combs like 1 antibody, KIAA0978 antibody, MGC71111 antibody, MGC117280 antibody.

Pathways: Retinoic Acid Receptor Signaling Pathway