RGS14 Antikörper (AA 223-251)

Produktnummer ABIN5534664

Der Kaninchen Polyklonal Anti-RGS14-Antikörper wurde für WB validiert. Er ist geeignet, RGS14 in Proben von Human zu detektieren.

Kurzübersicht für RGS14 Antikörper (AA 223-251) (ABIN5534664)

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RGS14 Antikörper

Bindungsspezifität: AA 223-251

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the Central region of human RGS14.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Andere Bezeichnung: RGS14

Hintergrund: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Molekulargewicht: 61 kDa

Gen-ID: 10636

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling