5HT1B Receptor Antikörper (AA 225-253)

Produktnummer ABIN5530220

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch 5HT1B Receptor in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für 5HT1B Receptor Antikörper (AA 225-253) (ABIN5530220)

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 5HT1B Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-5HT1B Receptor Antikörper

Bindungsspezifität: AA 225-253

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HTR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human HTR1B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Andere Bezeichnung: HTR1B

Hintergrund: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.

Molekulargewicht: 44 kDa

Gen-ID: 3351

UniProt: P28222

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteine