5HT1B Receptor Antikörper (Internal Region)

Produktnummer ABIN6256875

Produktdetails anti-5HT1B Receptor Antikörper

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 5HT1B Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: 5HT1B Receptor Antibody detects endogenous levels of total 5HT1B Receptor.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human 5HT1B Receptor, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Andere Bezeichnung: HTR1B (HTR1B Produkte)

Synonyme: 5-HT1B antikoerper, 5-HT1DB antikoerper, HTR1D2 antikoerper, HTR1DB antikoerper, S12 antikoerper, 5-HT1Db antikoerper, 5-HT1-LIKE antikoerper, HTR1B antikoerper, 5-HT-dro2B antikoerper, 5-HT1BDro antikoerper, 5-HT[1B]Dro antikoerper, 5-HT[[1BDro]] antikoerper, 5-HT[[1B]] antikoerper, 5-HT[[1B]]DRO antikoerper, 5-HT[[1B]]Dro antikoerper, 5-HT[[dro2B]] antikoerper, 5HT-R2B antikoerper, 5HT-dro2B antikoerper, 5HT-dro[[2B]] antikoerper, 5HT1B antikoerper, 5htdro2b antikoerper, CG15113 antikoerper, CG30126 antikoerper, DRO2B antikoerper, Dm5HTdro2B antikoerper, Dmel\\CG15113 antikoerper, Dmel_CG30126 antikoerper, d5-HT1B antikoerper, 5-HT-1B antikoerper, zgc:194666 antikoerper, zgc:194690 antikoerper, 5-hydroxytryptamine receptor 1B antikoerper, 5-hydroxytryptamine (serotonin) receptor 1B antikoerper, HTR1B antikoerper, Htr1b antikoerper, 5-HT1B antikoerper, htr1b antikoerper

Hintergrund:

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Gene: HTR1B

Molekulargewicht: 44 kDa

Gen-ID: 3351

UniProt: P28222

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteine