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VCAM1 Antikörper (AA 25-270)

VCAM1 Reaktivität: Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5519072
  • Target Alle VCAM1 Antikörper anzeigen
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Bindungsspezifität
    • 16
    • 15
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-270
    Reaktivität
    • 138
    • 106
    • 56
    • 25
    • 15
    • 8
    • 8
    • 4
    • 3
    • 1
    Maus, Ratte
    Wirt
    • 95
    • 76
    • 44
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 130
    • 90
    • 1
    Polyklonal
    Konjugat
    • 97
    • 27
    • 25
    • 14
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VCAM1 Antikörper ist unkonjugiert
    Applikation
    • 114
    • 109
    • 55
    • 42
    • 40
    • 35
    • 27
    • 26
    • 25
    • 16
    • 16
    • 12
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for VCAM1 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for VCAM1 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
    Gene Name: vascular cell adhesion molecule 1
    Protein Name: Vascular cell adhesion protein 1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived mouse VCAM1 recombinant protein (Position: F25-L270).
    Isotyp
    IgG
    Top Product
    Discover our top product VCAM1 Primärantikörper
  • Applikationshinweise
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Ma, Pan, Ren, Guo, Guo, Wei, Zheng, Chen: "15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell." in: Lipids in health and disease, Vol. 16, Issue 1, pp. 137, (2018) (PubMed).

    Wang, Qing, Liu, Liu, Qiao, Cui, He, Zhao, Liu, Yan, Wang, Liang, Guo, Shen, Hou, Chen: "Mesenchymal stromal cells ameliorate oxidative stress-induced islet endothelium apoptosis and functional impairment via Wnt4-β-catenin signaling." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 188, (2018) (PubMed).

    Hoffman, Adeli: "LDL Receptor Gene-Ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia with Dominant Inheritance and Diet-Induced Coronary Atherosclerosis." in: EBioMedicine, Vol. 28, pp. 17-18, (2018) (PubMed).

    Tian, Tao, Zhao, Tai, Liu, Liu: "Isolation and morphological characterization of ovine amniotic fluid mesenchymal stem cells." in: Experimental animals, Vol. 65, Issue 2, pp. 125-34, (2017) (PubMed).

    Ma, Pan, Chen, Guo, Zhao, Zheng, Chen: "Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion." in: Bioscience reports, Vol. 37, Issue 2, (2017) (PubMed).

    Chen, Zhang, Chen, Liu, Wang, Zhou, Qiu, Zhang, Teng, Mao, Liu, Wei, Li: "Retinoic Acid promotes interleukin-4 plasmid-dimethylsulfoxide topical transdermal delivery for treatment of psoriasis." in: Annals of dermatology, Vol. 27, Issue 2, pp. 121-7, (2015) (PubMed).

    Yu, Ge, Summers, Li, Liu, Ma, Kaminski, Zhuang: "TSP-1 secreted by bone marrow stromal cells contributes to retinal ganglion cell neurite outgrowth and survival." in: PLoS ONE, Vol. 3, Issue 6, pp. e2470, (2008) (PubMed).

  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Andere Bezeichnung
    Vcam1 (VCAM1 Produkte)
    Synonyme
    CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper
    Hintergrund
    CD106(cluster of differentiation 106) also known as vascular cell adhesion molecule 1(VCAM-1), is a protein that in humans is encoded by the VCAM1 gene. In inflammatory conditions and in cardiac allografts undergoing rejection, VCAM1 is upregulated in endothelium of postcapillary venules. Arterial expression of VCAM1 is also found in experimental models of atherosclerosis in the rabbit. This gene is mapped to chromosome 1 by Southern analysis of somatic cell hybrids. VCAM-1 functions as a cell adhesion molecule. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, andbasophils to vascularendothelium. It also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development ofatherosclerosis and rheumatoid arthritis. CAM741 works similar to cotransin in that it represses the biosynthesis of VCAM1 cells by blocking the process of cotranslational translocation, which is dependent on the signal peptide ofVCAM1. Among the lung metastasis signature genes identified, several, includingVCAM1, were functionally validated.

    Synonyms: Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, CD106, Vcam1, Vcam-1
    Gen-ID
    22329
    UniProt
    P29533
    Pathways
    Carbohydrate Homeostasis
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