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ITGAL Antikörper (AA 161-349)

ITGAL Reaktivität: Human FACS, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518766
  • Target Alle ITGAL Antikörper anzeigen
    ITGAL (Integrin alpha-L (ITGAL))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-349
    Reaktivität
    • 132
    • 76
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 104
    • 60
    • 49
    • 1
    Kaninchen
    Klonalität
    • 160
    • 53
    • 1
    Polyklonal
    Konjugat
    • 73
    • 29
    • 26
    • 21
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGAL Antikörper ist unkonjugiert
    Applikation
    • 139
    • 53
    • 35
    • 32
    • 32
    • 27
    • 24
    • 24
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Integrin alpha-L(ITGAL) detection. Tested with WB, FCM in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Integrin alpha-L(ITGAL) detection. Tested with WB, FCM in Human.
    Gene Name: integrin subunit alpha L
    Protein Name: Integrin alpha-L
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human CD11a recombinant protein (Position: F161-L349). Human CD11a shares 73.7% mino acid (aa) sequence identity with mouse CD11a.
    Isotyp
    IgG
    Top Product
    Discover our top product ITGAL Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Flow Cytometry: Concentration: 1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Mu, Jing, Guo: "Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." in: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).

  • Target
    ITGAL (Integrin alpha-L (ITGAL))
    Andere Bezeichnung
    ITGAL (ITGAL Produkte)
    Synonyme
    CD11A antikoerper, LFA-1 antikoerper, LFA1A antikoerper, (p180) antikoerper, Cd11a antikoerper, LFA-1A antikoerper, Ly-15 antikoerper, Ly-21 antikoerper, CD11a antikoerper, ITGAL antikoerper, integrin subunit alpha L antikoerper, integrin alpha L antikoerper, ITGAL antikoerper, Itgal antikoerper
    Hintergrund
    CD11a, also known as ITGAL or LFA-1, is a human gene which functions in the immune system. It is mapped to 16p11.2. CD11a is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. CD11a encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. It is one of the two components, along with CD18, which form lymphocyte function-associated antigen-1.

    Synonyms: Antigen CD11A | CD 11a | CD11 antigen-like family member A | CD11a antigen | Integrin alphaL | Integrin alpha-L | ITAL | ITGAL protein | LFA 1A | LFA1A | LFA-1A | P20701
    Gen-ID
    3683
    UniProt
    P20701
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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