PAX6 Antikörper (C-Term)

Produktnummer ABIN5517237

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAX6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Pferd, Hund, Meerschweinchen, Schwein und Schaf.

Kurzübersicht für PAX6 Antikörper (C-Term) (ABIN5517237)

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Pferd, Hund, Meerschweinchen, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAX6 Antikörper

Bindungsspezifität: C-Term

Sequenz: PSVNGRSYDT YTPPHMQTHM NSQPMGTSGT TSTGLISPGV SVPVQVPGSE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: PAX6

Hintergrund: This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: Name=PAX6,

Protein Interaction Partner: IPO13, Dlg4, NKIRAS2, Cacnb3, Pax6, Diap1, SMAD5, SMAD4, SMAD3, SMAD1, AR, HIPK2, SUMO1, SMARCA4, TP73, SHANK3, PBX1, VSX2, EN1, TRIM11, HOMER3, SIX3, INADL, EP300, SOX10, RGS3, DIAPH1, MAFG, RAX, DYNLL1, DLG1, CDX2, TBP, SOX3, MITF, HOXB1, SOX2, LHX2, TA

Protein Size: 422

Gen-ID: 5080

NCBI Accession: XP_005253013

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis