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NSUN2 Antikörper (N-Term)

NSUN2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5517213
  • Target Alle NSUN2 Antikörper anzeigen
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 27
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser NSUN2 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 19
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NSUN2. It was validated on Western Blot.
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2
    Top Product
    Discover our top product NSUN2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Andere Bezeichnung
    NSUN2 (NSUN2 Produkte)
    Synonyme
    D13Wsu123e antikoerper, Misu antikoerper, MISU antikoerper, MRT5 antikoerper, SAKI antikoerper, TRM4 antikoerper, RGD1311954 antikoerper, NOL1/NOP2/Sun domain family member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 antikoerper, NOP2/Sun RNA methyltransferase family, member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 S homeolog antikoerper, Nsun2 antikoerper, NSUN2 antikoerper, nsun2.S antikoerper
    Hintergrund
    NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

    Alias Symbols: NSUN2, SAKI, TRM4,

    Protein Interaction Partner: SUMO2, SUMO3, UBC, SUMO1, NEDD8, TP53RK, PUS1, EFTUD1, XPO5, UGGT1, OSGEP, PANK4, THG1L, SH3GLB1, KIAA1279, UBXN7, TTLL12, ARPC2, ACTR2, ACTR3, FUBP1, TSN, SH3GL1, RPA1, RDX, RANGAP1, PPP2CB, PFDN5, PFDN1, NRD1, PPP1R12A, HARS, GTF2E1, CALU, CALR, UBD, VC

    Protein Size: 767
    Gen-ID
    54888
    NCBI Accession
    NP_060225
    UniProt
    Q08J23
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