TUBGCP4 Antikörper (C-Term)

Produktnummer ABIN5516562

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TUBGCP4 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TUBGCP4 Antikörper (C-Term) (ABIN5516562)

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBGCP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TUBGCP4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TUBGCP4 Antibody - C-terminal region

Sequenz: KGFSRQSSLL FKILSSVRNH QINSDLAQLL LRLDYNKYYT QAGGTLGSFG

Produktmerkmale: This is a rabbit polyclonal antibody against GCP4. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75532-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TUBGCP4

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Andere Bezeichnung: TUBGCP4

Hintergrund:

Background Information: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.

Gene Name: tubulin gamma complex associated protein 4

Alternative Symbols: 76P, GCP4, GCP-4, Grip76, MCCRP3

Protein Name: gamma-tubulin complex component 4

Molekulargewicht: 73kDa

Gen-ID: 27229

UniProt: Q9UGJ1

Pathways: M Phase