COPS6 Antikörper (C-Term)

Produktnummer ABIN5516175

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COPS6 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für COPS6 Antikörper (C-Term) (ABIN5516175)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COPS6 Antikörper

Bindungsspezifität: C-Term

Sequenz: LILEYVKASE AGEVPFNHEI LREAYALCHC LPVLSTDKFK TDFYDQCNDV

Produktmerkmale: This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human COPS6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Andere Bezeichnung: COPS6

Hintergrund: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Alias Symbols: Name=COPS6,

Protein Interaction Partner: NEDD8, CUL1, UBC, COPS5, GPS1, SUMO1, POP7, COPS7B, COPS7A, CUL4B, USP7, COPS4, FBXO6, FBXW4, IGHV3OR15-7, vpr, TP63, RFWD2, SFN, IRF5, COPS8, COPS2, COPS3, DDB2, DDB1, ERCC8, TOR1AIP2, LRR1, RBX1, VPRBP, LRRC14, CUL2, CUL3, CUL4A, CUL5, TCEB2, TCEB1, SKP

Protein Size: 327

Gen-ID: 10980

NCBI Accession: NP_006824

UniProt: Q7L5N1

Pathways: Zellzyklus