MAPKAP Kinase 2 Antikörper (N-Term)

Produktnummer ABIN5516092

Der Kaninchen Polyklonal anti-MAPKAP Kinase 2 Antikörper wird verwendet zum Nachweis von MAPKAP Kinase 2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MAPKAP Kinase 2 Antikörper (N-Term) (ABIN5516092)

Target: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP Kinase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPKAP Kinase 2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAPKAPK2 Antibody - N-terminal region

Sequenz: SNSQGQSPPV PFPAPAPPPQ PPTPALPHPP AQPPPPPPQQ FPQFHVKSGL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAPKAPK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74632-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPKAP Kinase 2

Target: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Andere Bezeichnung: MAPKAPK2

Hintergrund:

Background Information: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Gene Name: mitogen-activated protein kinase-activated protein kinase 2

Alternative Symbols: MK2, MK-2, MAPKAP-K2

Protein Name: MAP kinase-activated protein kinase 2

Molekulargewicht: 44 kDa

Gen-ID: 9261

NCBI Accession: NP_004750

UniProt: P49137

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades