MAPK7 Antikörper (N-Term)

Produktnummer ABIN5516013

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAPK7 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MAPK7 Antikörper (N-Term) (ABIN5516013)

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPK7 Antikörper

Bindungsspezifität: N-Term

Sequenz: PLKEEDGEDG SAEPPGPVKA EPAHTAASVA AKNLALLKAR SFDVTFDVGD

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAPK7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPK7

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Andere Bezeichnung: MAPK7

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Alias Symbols: BMK1, ERK4, ERK5, PRKM7

Protein Size: 816

Gen-ID: 5598

NCBI Accession: NM_002749, NP_002740

UniProt: Q13164

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling