PSMA7 Antikörper (C-Term)

Produktnummer ABIN5515527

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PSMA7 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PSMA7 Antikörper (C-Term) (ABIN5515527)

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PSMA7 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PSMA7 Antibody - C-terminal region

Sequenz: VQSGGKNIEL AVMRRDQSLK ILNPEEIEKY VAEIEKEKEE NEKKKQKKAS

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMA7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76502-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMA7

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Andere Bezeichnung: PSMA7

Hintergrund:

Background Information: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Gene Name: Proteasome subunit alpha 7

Alternative Symbols: C6, HSPC, RC6-1, XAPC7, HEL-S-276

Protein Name: proteasome subunit alpha type-7

Molekulargewicht: 28 kDa

Gen-ID: 5688

NCBI Accession: NP_002783

UniProt: O14818

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA