PKM Antikörper (C-Term)

Produktnummer ABIN5514803

Der Kaninchen Polyklonal anti-PKM Antikörper (ABIN5514803) detektiert spezifisch PKM in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PKM Antikörper (C-Term) (ABIN5514803)

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKM Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PKM Antibody - C-terminal region

Sequenz: VICATQMLES MIKKPRPTRA EGSDVANAVL DGADCIMLSG ETAKGDYPLE

Produktmerkmale: This is a rabbit polyclonal antibody against KPYM. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KPYM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75032-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PKM

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Andere Bezeichnung: PKM

Hintergrund:

Background Information: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Gene Name: pyruvate kinase M1/2

Alternative Symbols: PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30

Protein Name: pyruvate kinase PKM

Molekulargewicht: 58kDa

Gen-ID: 5315

NCBI Accession: XP_005254502

UniProt: P14618

Pathways: Warburg Effekt