TPP1 Antikörper (C-Term)

Produktnummer ABIN5514672

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TPP1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TPP1 Antikörper (C-Term) (ABIN5514672)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TPP1 Antikörper

Bindungsspezifität: C-Term

Sequenz: QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: TPP1

Hintergrund: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1

Protein Size: 563

Gen-ID: 1200

NCBI Accession: NM_000391, NP_000382

UniProt: O14773

Pathways: Zellzyklus, ER-Nucleus Signaling