Apolipoprotein C-II Antikörper (Middle Region)
Kurzübersicht für Apolipoprotein C-II Antikörper (Middle Region) (ABIN5514502)
Target
Alle Apolipoprotein C-II (APOC2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- ESAKTAAQNL YEKTYLPAVD EKLRDLYSKS TAAMSTYTGI FTDQVLSVLK
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Homologie
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against APOC2. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human APOC2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Apolipoprotein C-II (APOC2)
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Andere Bezeichnung
- APOC2
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Hintergrund
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This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
Alias Symbols: APOC2, APC2,
Protein Interaction Partner: CRYAB, ALB, LPL,
Protein Size: 101 -
Gen-ID
- 344
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NCBI Accession
- NP_000474
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UniProt
- P02655
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Pathways
- Lipid Metabolism
Target
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