Apolipoprotein C-II Antikörper (AA 1-101)

Produktnummer ABIN3022521

Der Kaninchen Polyklonal anti-Apolipoprotein C-II Antikörper (ABIN3022521) detektiert spezifisch Apolipoprotein C-II in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Apolipoprotein C-II Antikörper (AA 1-101) (ABIN3022521)

Target: Apolipoprotein C-II (APOC2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apolipoprotein C-II Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Apolipoprotein C-II Antikörper

Bindungsspezifität: AA 1-101

Sequenz: MGTRLLPALF LVLLVLGFEV QGTQQPQQDE MPSPTFLTQV KESLSSYWES AKTAAQNLYE KTYLPAVDEK LRDLYSKSTA AMSTYTGIFT DQVLSVLKGE E

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human APOC2 (NP_000474.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Apolipoprotein C-II

Target: Apolipoprotein C-II (APOC2)

Andere Bezeichnung: APOC2

Hintergrund: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.,APOC2,APO-CII,APOC-II,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Lipids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,APOC2

Molekulargewicht: 11 kDa

Gen-ID: 344

UniProt: P02655

Pathways: Lipid Metabolism