ANAPC5 Antikörper (Middle Region)

Produktnummer ABIN5514501

Produktdetails anti-ANAPC5 Antikörper

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HSLLHYFDRL ILTGAESKSN GEEGYGRSLR YAALNLAALH CRFGHYTSPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANAPC5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ANAPC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Andere Bezeichnung: ANAPC5 (ANAPC5 Produkte)

Synonyme: APC5 antikoerper, DDBDRAFT_0206386 antikoerper, DDBDRAFT_0234269 antikoerper, DDB_0206386 antikoerper, DDB_0234269 antikoerper, zgc:55800 antikoerper, wu:fb75a09 antikoerper, ANAPC5 antikoerper, MGC89697 antikoerper, 2510006G12Rik antikoerper, AA408751 antikoerper, AA536819 antikoerper, AA986414 antikoerper, Anpc5 antikoerper, F12K11.7 antikoerper, F12K11_7 antikoerper, anaphase promoting complex subunit 5 antikoerper, anaphase-promoting complex subunit 5 antikoerper, anaphase promoting complex subunit 5 L homeolog antikoerper, anaphase-promoting complex subunit antikoerper, anaphase-promoting complex subunit Apc5 antikoerper, ANAPC5 antikoerper, anapc5 antikoerper, LOC100093215 antikoerper, anapc5.L antikoerper, Anapc5 antikoerper, AT1G06590 antikoerper, apc5 antikoerper

Hintergrund: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Alias Symbols: ANAPC5, APC5,

Protein Interaction Partner: ANAPC2, UBE2S, UBC, ANAPC4, HECW2, LATS2, PHF8, SOX2, PTEN, CDC27, BACH1, TRIM33, ANAPC7, ANAPC15, CDH1, CDC20, PAXIP1, MDC1, TP53BP1, NOTCH1, ANAPC1, ANAPC13, CDC16, CDC23, FBXO5, USP37, CUL4A, SH3KBP1, E2F1, SMARCAD1, MAPK6, Gm9174, Anapc5, Mad2l1, Anap

Protein Size: 219

Gen-ID: 51433

Pathways: M Phase