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AIM2 Antikörper (AA 1-343)

Name: AIM2 Antikörper (AA 1-343)
SKU: ABIN522906
Price: 693.44 EUR
Availability: InStock

AIM2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated

Western Blot analysis of AIM2 expression in transfected 293T cell line by AIM2 MaxPab polyclonal antibody. (AIM2 Antikörper (AA 1-343))

Immunofluorescence of purified MaxPab antibody to AIM2 on HeLa cell. (AIM2 Antikörper (AA 1-343))

2 Abbildungen

(4 Referenzen)

Produktnummer ABIN522906

Datenblatt (PDF)

Target Alle AIM2 Antikörper anzeigen

AIM2 (Absent in Melanoma 2 (AIM2))
Bindungsspezifität
16

8

7

5

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-343
Reaktivität
70

25

19

3

3

1
Human
Wirt
57

12

2
Maus
Passende Sekundärantikörper
Klonalität
61

10
Polyklonal
Konjugat
38

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser AIM2 Antikörper ist unkonjugiert
Applikation
58

30

30

18

13

13

11

10

6

5

3

2

2

1
Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck

Mouse polyclonal antibody raised against a full-length human AIM2 protein.

Sequenz

MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT

Kreuzreaktivität

Human

Produktmerkmale

Antibody reactive against mammalian transfected lysate.

Immunogen

AIM2 (NP_004824, 1 a.a. ~ 343 a.a) full-length human protein.

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anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibody
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anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibody
AIM2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

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AIM2 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibody
AIM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

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AIM2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Ansari, Singh, Dutta, Veettil, Dutta, Chikoti, Lu, Everly, Chandran: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." in: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).

Lee, Li, Gretz, Gebert, Dihlmann: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." in: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).

Wang, Hsu, Chen, Liang, Chen, Ojcius, Tsang, Hsueh, Wu, Chang: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).

Fernandes-Alnemri, Yu, Datta, Wu, Alnemri: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." in: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).
Target

AIM2 (Absent in Melanoma 2 (AIM2))

Andere Bezeichnung

AIM2 (AIM2 Produkte)

Hintergrund

Full Gene Name: absent in melanoma 2
Synonyms: PYHIN4

Gen-ID

9447

NCBI Accession

NM_004833

Pathways

Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome