HLA-B Antikörper (AA 1-362)

Produktnummer ABIN516466

Produktdetails anti-HLA-B Antikörper

Target: HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))

Bindungsspezifität: AA 1-362

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser HLA-B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human HLA-B protein.

Sequenz: MRVTAPRTVL LLLSGALALT ETWAGSHSMR YFYTAMSRPG RGEPRFISVG YVDDTQFVRF DSDAASPREE PRAPWIEQEG PEYWDRNTQI CKTNTQTYRE SLRNLRGYYN QSEAGSHTLQ RMYGCDVGPD GRLLRGHDQY AYDGKDYIAL NEDLSSWTAA DTAAQITQRK WEAAREAEQL RAYLEGLCVE WLRRYLENGK ETLQRADPPK THVTHHPISD HEATLRCWAL GFYPAEITLT WQRDGEDQTQ DTELVETRPA GDRTFQKWAA VVVPSGEEQR YTCHVQHEGL PKPLTLRWEP SSQSTIPIVG IVAGLAVLAV VVIGAVVATV MCRRKSSGGK GGSYSQAASS DSAQGSDVSL TA

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: HLA-B (AAH13187.1, 1 a.a. ~ 362 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HLA-B Antikörper (ABIN516466)

Lorente, Infantes, Abia, Barnea, Beer, García, Lasala, Jiménez, Mir, Morreale, Admon, López et al.: "A viral, transporter associated with antigen processing (TAP)-independent, high affinity ligand with alternative interactions endogenously presented by the nonclassical human leukocyte antigen E ..." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 34895-903, (2012) (PubMed).

Lorente, García, López: "Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38054-9, (2011) (PubMed).

Lorente, Infantes, Barnea, Beer, García, Lasala, Jiménez, Vilches, Lemonnier, Admon, López: "Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells." in: Journal of virology, Vol. 86, Issue 1, pp. 527-41, (2011) (PubMed).

Details zu HLA-B

Target: HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))

Andere Bezeichnung: HLA-B (HLA-B Produkte)

Hintergrund: Full Gene Name: major histocompatibility complex, class I, B
Synonyms: AS,HLA-B-7301,HLA-B73,HLAB,HLAC,SPDA1

Gen-ID: 3106

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response