Optimal working dilutions should be determined experimentally by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
-20 °C
Target
LGR5
(Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
Andere Bezeichnung
GPR49
Hintergrund
GPR49 is an orphaned member of the glycoprotein hormone receptor subfamily. It is thought to play an important role in growth and differentiation of embyronic tissue. It is highly expressed in the brain, spinal cord, placenta, and skeletal muscle. GPR49 is up-regulated in several cancers. It is also thought to be a target gene activated by Wnt-signaling.