MLH1 Antikörper (AA 289-492)
Kurzübersicht für MLH1 Antikörper (AA 289-492) (ABIN5027360)
Target
Alle MLH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 289-492
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Aufreinigung
- Protein G Chromatography
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Immunogen
- A partial length recombinant MLH1 protein (amino acids 289-492) was used as the immunogen for this antibody.
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Isotyp
- IgG2b
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Applikationshinweise
- IHC: 5-10 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MLH1 (MutL Homolog 1 (MLH1))
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Andere Bezeichnung
- MLH1
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Hintergrund
- MutL homolog 1 (MLH1) is a member of mismatch repair genes (MMR) that plays a crucial role in correcting replication errors, cell cycle arrest, apoptosis and oxidative stress. MLH1 is a human homolog of the E.coli DNA mismatch repair gene. It mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Diseases associated with MLH1 include colorectal cancer, hereditary nonpolyposis, type 2 and lynch syndrome.
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Gen-ID
- 4292
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UniProt
- P40692
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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