DLL4 Antikörper (AA 423-650)

Produktnummer ABIN5027156

Dieses Anti-DLL4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLL4 in WB. Geeignet für Human.

Kurzübersicht für DLL4 Antikörper (AA 423-650) (ABIN5027156)

Target: DLL4 (delta-Like 4 (DLL4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DLL4 Antikörper

Bindungsspezifität: AA 423-650

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant DLL4 protein (amino acids 423-650) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: DLL4

Hintergrund: Dll4 (Delta-like 4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. It is highly expressed in capillary endothelial tip cells and is involved in suppressing neighboring stalk cells to become tip cells during angiogenesis. Dll4-Notch signaling is mediated either by direct cell-cell contact or by Dll4-containing exosomes from a distance. DLL4 signaling is extensively critical for tumor angiogenesis. Blockage of DLL4 signaling inhibits tumor growth by deregulating angiogenesis and promoting non productive angiogenesis. Additionally, DLL4 has been shown to help regulate the cellular actions of VEGF.

Molekulargewicht: 75 kDa

Gen-ID: 54567

UniProt: Q9NR61

Pathways: Notch Signalweg