CYLD Antikörper (AA 1-230)
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- Target Alle CYLD Antikörper anzeigen
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Bindungsspezifität
- AA 1-230
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYLD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein A Chromatography
- Immunogen
- A partial length recombinant CYLD protein (amino acids 1-230 ) was used as the immunogen for this antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CYLD Primärantikörper
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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 170-338) antibody
CYLD Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibodyCYLD Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibodyCYLD Reaktivität: Human, Maus WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibodyCYLD Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5F7F4 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibodyCYLD Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibodyCYLD Reaktivität: Human, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibodyCYLD Reaktivität: Human, Maus, Hamster, Huhn, Rind (Kuh), Hund, Meerschweinchen, Pferd, Affe, Kaninchen WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 305-582) antibodyCYLD Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 1667CT857-3-6-1 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibodyCYLD Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 3A9 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibodyCYLD Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 2C3 unconjugated
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- Applikationshinweise
- WB: 2-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Andere Bezeichnung
- CYLD (CYLD Produkte)
- Hintergrund
- CYLD (Ubiquitin carboxyl-terminal hydrolase) belongs to peptidase C19 family with 956 amino acids. It is a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains which function as a deubiquitinating enzyme which specifically cleaves 'Lys-63'-linked polyubiquitin chains and 1 ubiquitin-specific proteases (USP) domain. CYLD plays an important role in the regulation of pathways leading to NF-kappa-B activation, proliferation and differentiation. It also interacts with (via CAP-Gly domain) IKBKG/NEMO (via proline-rich C-terminal region). CYLD is important for the survival of immature natural killer cells whereas it is not required for the maturation of intrathymic natural killer cells. It is detected in fetal brain, testis and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. CYLD related diseases are multiple familial trichoepithelioma 1 and familial cylindromatosis.
- Molekulargewicht
- 105 kDa
- Gen-ID
- 1540
- UniProt
- Q9NQC7
- Pathways
- Apoptose, Activation of Innate immune Response
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