Cyclin D1 Antikörper (AA 108-322)
Kurzübersicht für Cyclin D1 Antikörper (AA 108-322) (ABIN5027124)
Target
Alle Cyclin D1 (CCND1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 108-322
-
Aufreinigung
- Protein G Chromatography
-
Immunogen
- A partial length recombinant Cyclin D1 protein (amino acids 108-322) was used as the immunogen for this antibody.
-
Isotyp
- IgG2a kappa
-
-
anti-Cyclin D1 (CCND1) (AA 61-110) antibody
CCND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB8066 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyKO Validated CCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 167-295) antibodyCCND1 Reaktivität: Human IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 3B6G3 unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 Reaktivität: Human, Maus WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 1F7F5 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 Reaktivität: Human, Maus WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyCCND1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal DCS-6 unconjugated
-
-
Applikationshinweise
- IHC: 5-10 μg/mL
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 0.5 mg/mL
-
Buffer
- PBS containing 0.05 % BSA, PH 7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- Cyclin D1 (CCND1)
-
Andere Bezeichnung
- Cyclin D1
-
Hintergrund
- Cyclin D1 (CCND1) is an important positive regulator of the G1/S phase of the cell cycle. It regulate cell cycle transition from G1 phase to S phase It is a well-established human oncogene which is frequently amplified or overexpressed in cancers (25409185). Cyclin D1b is one of two proteins translated from Cyclin D1 transcripts (isoforms a and b) that are generated due to gene polymorphism. Low Cyclin D1b expression in cervical cancer tissue, with an expression level in moderately or poorly differentiated tissues was significantly lower than that in well-differentiated tissues (25120779). Diseases associated with CCND1 include multiple myeloma and mantle cell lymphoma.
-
Gen-ID
- 23582
-
UniProt
- O95273
-
Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
Target
-
