Caspase 12 Antikörper (AA 100-321)
Kurzübersicht für Caspase 12 Antikörper (AA 100-321) (ABIN5027075)
Target
Alle Caspase 12 (CASP12) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-321
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Aufreinigung
- Protein A Chromatography
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Immunogen
- A partial length recombinant Caspase-12 protein (amino acids 100-321) was used as the immunogen for this antibody.
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Isotyp
- IgG
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Applikationshinweise
- WB: 4-6 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
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Andere Bezeichnung
- Caspase-12
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Hintergrund
- Caspase 12 belongs to a family of enzymes called caspases that is highly related to members of the ICE subfamily. Other caspases cleave their substrates at C-terminal aspartic acid residue but caspase 12 does not have protease properties rather it processes inflammatory cytokines. It is involved in the activation cascade of caspases responsible for apoptosis execution. Diseases associated with CASP12 include sepsis and prion disease. Caspase 12 is mainly expressed in skeletal muscle and lung.
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Molekulargewicht
- 27 kDa
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Gen-ID
- 101000000
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UniProt
- Q6UXS9
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Pathways
- Apoptose, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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