Thymidine Phosphorylase Antikörper (AA 121-220) (AbBy Fluor® 750)

Produktnummer ABIN5011816

Der Kaninchen Polyklonal Anti-Thymidine Phosphorylase-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Thymidine Phosphorylase in Proben von Human zu detektieren.

Kurzübersicht für Thymidine Phosphorylase Antikörper (AA 121-220) (AbBy Fluor® 750) (ABIN5011816)

Target: Thymidine Phosphorylase (TYMP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thymidine Phosphorylase Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Thymidine Phosphorylase Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 121-220

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Thymidine Phosphorylase

Target: Thymidine Phosphorylase (TYMP)

Andere Bezeichnung: TP/thymidine phosphorylase

Hintergrund:

Synonyms: ECGF 1, PDEGF, ECGF1, Endothelial cell growth factor 1, Endothelial cell growth factor 1 platelet derived, Gliostatin, hPD ECGF, MNGIE, PD ECGF, PDECGF, PDEGF, Platelet derived endothelial growth factor, TdRPase, TP, TYMP, Thymidine Phosphorylase, TYPH_HUMAN, TdRPase.

Background: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Gen-ID: 1890

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2