TLR3 Antikörper (AA 801-905) (AbBy Fluor® 680)
Kurzübersicht für TLR3 Antikörper (AA 801-905) (AbBy Fluor® 680) (ABIN5011659)
Target
Alle TLR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 801-905
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Kreuzreaktivität
 - Human, Maus, Ratte
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Homologie
 - Dog,Pig
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic peptide derived from mouse TLR3
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Isotyp
 - IgG
 
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Applikationshinweise
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                        FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
 - 12 months
 
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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Andere Bezeichnung
 - TLR3
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Hintergrund
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Synonyms: AI957183, Toll-like receptor 3, CD283, Tlr3
Background: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).
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Gen-ID
 - 142980
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UniProt
 - Q99MB1
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Pathways
 - TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
 
Target
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