Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TRIM5 Antikörper (C-Term, Isoform delta)

TRIM5 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501058
  • Target Alle TRIM5 Antikörper anzeigen
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Bindungsspezifität
    • 12
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, Isoform delta
    Reaktivität
    • 45
    • 4
    • 4
    • 1
    • 1
    Human
    Wirt
    • 39
    • 4
    • 2
    Kaninchen
    Klonalität
    • 40
    • 4
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser TRIM5 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 28
    • 10
    • 9
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TRIM5 / RNF88 delta.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TRIM5 delta antibody was raised against a synthetic peptide corresponding to 13 amino acids near the carboxy-terminus of human TRIM5 delta.
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM5 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 1 to 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Andere Bezeichnung
    TRIM5 / RNF88 (TRIM5 Produkte)
    Synonyme
    TRIM5 antikoerper, RNF88 antikoerper, TRIM5alpha antikoerper, EG667823 antikoerper, Gm8833 antikoerper, RGD1304579 antikoerper, tripartite motif containing 5 antikoerper, tripartite motif-containing 5 antikoerper, TRIM5 antikoerper, Trim5 antikoerper
    Hintergrund
    TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region (1). TRIM5 has five alternately spliced isoforms, the longest of which is the ? variant which also contains a carboxy-terminal B30.2 (SPRY) domain (1). Expression of TRIM5α variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1 (2,3), albeit at differing efficiencies. The TRIM5δ isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5δ also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner (4).Synonyms: RING finger protein 88, Tripartite motif-containing protein 5
    Gen-ID
    85363
    NCBI Accession
    NP_149084
    Pathways
    Activation of Innate immune Response
Sie sind hier:
Kundenservice