TLR8 Antikörper (Middle Region)

Produktnummer ABIN500964

Dieses Anti-TLR8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR8 in WB, IF und EIA. Geeignet für Human und Maus.

Kurzübersicht für TLR8 Antikörper (Middle Region) (ABIN500964)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody detects CD288 / TLR8 at center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Peptide affinity chromatography

Immunogen: TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: CD288 / TLR8

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).Synonyms: Toll-like receptor 8, UNQ249/PRO286

Gen-ID: 51311

NCBI Accession: NP_619542

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades