TLR6 Antikörper (N-Term)

Produktnummer ABIN500958

Dieses Anti-TLR6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR6 in WB, IF und EIA. Geeignet für Human und Maus.

Kurzübersicht für TLR6 Antikörper (N-Term) (ABIN500958)

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR6 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects CD286 / TLR6 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Andere Bezeichnung: CD286 / TLR6

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69 % sequence identify (4). Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan (5). Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses (6).Synonyms: Toll-like receptor 6

Gen-ID: 10333

NCBI Accession: NP_006059

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades