TLR3 Antikörper (C-Term)

Produktnummer ABIN500948

Der Kaninchen Polyklonal Anti-TLR3-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, TLR3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für TLR3 Antikörper (C-Term) (ABIN500948)

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR3 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects CD283 / TLR3 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Ion exchange chromatography

Immunogen: TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR3

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Andere Bezeichnung: CD283 / TLR3

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection (4). Recently it has been shown to recognize viruses such as Influenza A (5) and West Nile Virus and can mediate entry of at least West Nile Virus (6).Synonyms: Toll-like receptor 3

Gen-ID: 7098

UniProt: O15455

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades